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HAZMAT is an acronym for hazardous materials or the safety programs instituted to protect the public from exposure to hazardous materials.

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Various federal agencies have developed regulations regarding the transportation and disposal of hazardous materials, including the Department of Transportation (DOT), the Environmental Protection Agency (EPA), and the Occupational Safety and Health Administration (OSHA). The precise definition of hazardous materials varies depending on the regulatory agency. Truckers, contractors, and other entities must adhere to specific regulations regarding their use, transportation, and disposal of hazardous materials.